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Effect of mutation of a calmodulin binding site on Ca2+ regulation of inositol trisphosphate receptors.

Several studies have shown that calmodulin (CaM) modulates d-myo-inositol 1,4,5-trisphosphate (IP(3)) receptor (IP(3)R) channel activity and ligand binding to IP(3)Rs. It has been proposed that CaM may act as the Ca(2+) sensor for mediating Ca(2+) inhibition of IP(3)R channel activity. However, the...

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Bibliografiske detaljer
Main Authors: Zhang, X, Joseph, S K
Format: Artigo
Sprog:Inglês
Udgivet: 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222240/
https://ncbi.nlm.nih.gov/pubmed/11716768
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