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Effect of mutation of a calmodulin binding site on Ca2+ regulation of inositol trisphosphate receptors.
Several studies have shown that calmodulin (CaM) modulates d-myo-inositol 1,4,5-trisphosphate (IP(3)) receptor (IP(3)R) channel activity and ligand binding to IP(3)Rs. It has been proposed that CaM may act as the Ca(2+) sensor for mediating Ca(2+) inhibition of IP(3)R channel activity. However, the...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1222240/ https://ncbi.nlm.nih.gov/pubmed/11716768 |
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