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Targeting the prostate for destruction through a vascular address

Organ specific drug targeting was explored in mice as a possible alternative to surgery to treat prostate diseases. Peptides that specifically recognize the vasculature in the prostate were identified from phage-displayed peptide libraries by selecting for phage capable of homing into the prostate a...

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Detalhes bibliográficos
Main Authors: Arap, Wadih, Haedicke, Wolfgang, Bernasconi, Michele, Kain, Renate, Rajotte, Daniel, Krajewski, Stanislaw, Ellerby, H. Michael, Bredesen, Dale E., Pasqualini, Renata, Ruoslahti, Erkki
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122224/
https://ncbi.nlm.nih.gov/pubmed/11830668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.241655998
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