Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamily.

The glutathione transferases (GSTs; also known as glutathione S-transferases) are major phase II detoxification enzymes found mainly in the cytosol. In addition to their role in catalysing the conjugation of electrophilic substrates to glutathione (GSH), these enzymes also carry out a range of other...

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Main Authors: Sheehan, D, Meade, G, Foley, V M, Dowd, C A
Format: Artigo
Jezik:Inglês
Izdano: 2001
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222196/
https://ncbi.nlm.nih.gov/pubmed/11695986
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