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HemK, a class of protein methyl transferase with similarity to DNA methyl transferases, methylates polypeptide chain release factors, and hemK knockout induces defects in translational termination

HemK, a universally conserved protein of unknown function, has high amino acid similarity with DNA-(adenine-N6) methyl transferases (MTases). A certain mutation in hemK gene rescues the photosensitive phenotype of a ferrochelatase-deficient (hemH) mutant in Escherichia coli. A hemK knockout strain o...

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Publikašuvnnas:Proc Natl Acad Sci U S A
Váldodahkkit: Nakahigashi, Kenji, Kubo, Naoko, Narita, Shin-ichiro, Shimaoka, Takeshi, Goto, Simon, Oshima, Taku, Mori, Hirotada, Maeda, Maki, Wada, Chieko, Inokuchi, Hachiro
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: National Academy of Sciences 2002
Fáttát:
Biological Sciences
Liŋkkat:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122215/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11805295/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.032488499
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