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Urokinase-catalysed cleavage of the urokinase receptor requires an intact glycolipid anchor.

Urokinase (uPA) has the striking ability to cleave its receptor, uPAR, thereby inactivating the binding potential of this molecule. Here we demonstrate that the glycosylphosphatidylinositol (GPI) anchor of uPAR, which is attached to the third domain, is an important determinant in governing this rea...

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Detalhes bibliográficos
Main Authors: Høyer-Hansen, G, Pessara, U, Holm, A, Pass, J, Weidle, U, Danø, K, Behrendt, N
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222101/
https://ncbi.nlm.nih.gov/pubmed/11535128
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