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Dimethyl sulphoxide enhances the effects of P(i) in myofibrils and inhibits the activity of rabbit skeletal muscle contractile proteins.

In the catalytic cycle of skeletal muscle, myosin alternates between strongly and weakly bound cross-bridges, with the latter contributing little to sustained tension. Here we describe the action of DMSO, an organic solvent that appears to increase the population of weakly bound cross-bridges that a...

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Detalhes bibliográficos
Main Authors: Mariano, A C, Alexandre, G M, Silva, L C, Romeiro, A, Cameron, L C, Chen, Y, Chase, P B, Sorenson, M M
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222097/
https://ncbi.nlm.nih.gov/pubmed/11535124
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