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Adenovirus-mediated gene delivery and in vitro microinsemination produce offspring from infertile male mice

Sertoli cells play a pivotal role in spermatogenesis through their interactions with germ cells. To set up a strategy for treating male infertility caused by Sertoli cell dysfunction, we developed a Sertoli cell gene transfer system by using an adenovirus vector, which maintained long-term transgene...

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Main Authors: Kanatsu-Shinohara, Mito, Ogura, Atsuo, Ikegawa, Masaya, Inoue, Kimiko, Ogonuki, Narumi, Tashiro, Kei, Toyokuni, Shinya, Honjo, Tasuku, Shinohara, Takashi
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC122199/
https://ncbi.nlm.nih.gov/pubmed/11818536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022646399
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