Asparagine synthetase expression alone is sufficient to induce l-asparaginase resistance in MOLT-4 human leukaemia cells.

Childhood acute lymphoblastic leukaemia (ALL) is treated by combination chemotherapy with a number of drugs, always including the enzyme L-asparaginase (ASNase). Although the initial remission rate is quite high, relapse and associated drug resistance are a significant problem. In vitro studies have...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Aslanian, A M, Fletcher, B S, Kilberg, M S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2001
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221958/
https://ncbi.nlm.nih.gov/pubmed/11415466
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