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Thrombopoietin stimulates cortactin translocation to the cytoskeleton independently of tyrosine phosphorylation.

Cortactin is an F-actin-binding protein expressed in platelets. During aggregation by thrombin, cortactin associates with Src, is tyrosine phosphorylated, and then translocates to the cytoskeleton. It is also found to associate with Syk during platelet shape change. Since cortactin undergoes tyrosin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lopez, I, Duprez, V, Melle, J, Dreyfus, F, Lévy-Tolédano, S, Fontenay-Roupie, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2001
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221916/
https://ncbi.nlm.nih.gov/pubmed/11389697
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