Highly sensitive and selective fluorescence assays for rapid screening of endothelin-converting enzyme inhibitors.

The highly potent vasoconstrictor peptide endothelin (ET) is generated from an inactive precursor, big endothelin (bET), by endothelin-converting enzyme (ECE). ECE is a phosphoramidon-sensitive zinc metallopeptidase, which is closely related to neprilysin (neutral endopeptidase). It is possible that...

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Библиографические подробности
Главные авторы: Luciani, N, de Rocquigny, H, Turcaud, S, Romieu, A, Roques, B P
Формат: Artigo
Язык:Inglês
Опубликовано: 2001
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221908/
https://ncbi.nlm.nih.gov/pubmed/11389689
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