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Highly sensitive and selective fluorescence assays for rapid screening of endothelin-converting enzyme inhibitors.
The highly potent vasoconstrictor peptide endothelin (ET) is generated from an inactive precursor, big endothelin (bET), by endothelin-converting enzyme (ECE). ECE is a phosphoramidon-sensitive zinc metallopeptidase, which is closely related to neprilysin (neutral endopeptidase). It is possible that...
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主要な著者: | , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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2001
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1221908/ https://ncbi.nlm.nih.gov/pubmed/11389689 |
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