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Conformational landscape of cytochrome c folding studied by microsecond-resolved small-angle x-ray scattering

To investigate protein folding dynamics in terms of compactness, we developed a continuous-flow mixing device to make small-angle x-ray scattering measurements with the time resolution of 160 μs and characterized the radius of gyration (R(g)) of two folding intermediates of cytochrome c (cyt c). The...

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Détails bibliographiques
Auteurs principaux: Akiyama, Shuji, Takahashi, Satoshi, Kimura, Tetsunari, Ishimori, Koichiro, Morishima, Isao, Nishikawa, Yukihiro, Fujisawa, Tetsuro
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC122190/
https://ncbi.nlm.nih.gov/pubmed/11773620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.012458999
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