The enthalpy of the alanine peptide helix measured by isothermal titration calorimetry using metal-binding to induce helix formation

The goal of this study is to use the model system described earlier to make direct measurements of the enthalpy of helix formation at different temperatures. For this we studied model alanine peptides in which helix formation can be triggered by metal (La(3+)) binding. The heat of La(3+) interaction...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Lopez, Maria M., Chin, Der-Hang, Baldwin, Robert L., Makhatadze, George I.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2002
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122184/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11818561/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.032665199
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