Occurrence of paradoxical or sustained control by an enzyme when overexpressed: necessary conditions and experimental evidence with regard to hepatic glucokinase.

It is widely assumed that the control coefficient of an enzyme on pathway flux decreases as the concentration of enzyme increases. However, it has been shown [Kholodenko and Brown (1996) Biochem. J. 314, 753-760] that enzymes with sigmoidal kinetics can maintain or even gain control with an increase...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: De Atauri, P, Acerenza, L, Kholodenko, B N, De La Iglesia, N, Guinovart, J J, Agius, L, Cascante, M
Format: Artigo
Idioma:Inglês
Publicat: 2001
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221796/
https://ncbi.nlm.nih.gov/pubmed/11311143
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars