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Spectral and metal-binding properties of three single-point tryptophan mutants of the human transferrin N-lobe.

Human serum transferrin N-lobe (hTF/2N) contains three conserved tryptophan residues, Trp(8), Trp(128) and Trp(264), located in three different environments. The present report addresses the different contributions of the three tryptophan residues to the UV-visible, fluorescence and NMR spectra of h...

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Autori principali: He, Q Y, Mason, A B, Lyons, B A, Tam, B M, Nguyen, V, MacGillivray, R T, Woodworth, R C
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221671/
https://ncbi.nlm.nih.gov/pubmed/11171122
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