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Iron release from recombinant N-lobe and single point Asp63 mutants of human transferrin by EDTA.

Transferrins bind ferric ion and deliver the iron to cells. The mechanism of the iron release has been studied kinetically, in vitro, with the aid of single point mutants in which the iron-binding ligand, Asp63 (aspartic acid-63, D63), has been changed to Ser, Asn, Glu and Ala. Iron release from the...

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Autores principales: He, Q Y, Mason, A B, Woodworth, R C
Formato: Artigo
Lenguaje:Inglês
Publicado: 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218939/
https://ncbi.nlm.nih.gov/pubmed/9371699
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