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Overexpression of a rat kinase-deficient phosphoinositide 3-kinase, Vps34p, inhibits cathepsin D maturation.

Lipid kinases and their phosphorylated products are important regulators of many cellular processes, including intracellular membrane traffic. The best example of this is provided by the class III phosphoinositide 3-kinase (PI-3K), Vps34p, which is required for correct targeting of newly synthesized...

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Hlavní autoři: Row, P E, Reaves, B J, Domin, J, Luzio, J P, Davidson, H W
Médium: Artigo
Jazyk:Inglês
Vydáno: 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221612/
https://ncbi.nlm.nih.gov/pubmed/11171063
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