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Self-generated DNA termini relax the specificity of SgrAI restriction endonuclease
The primary target of SgrAI restriction endonuclease is a multiple sequence of the form 5′-CPu↓CCGGPyG. Previous work had indicated that SgrAI must bind two recognition sites simultaneously for catalysis [Bilcock, D. T., Daniels, L. E., Bath, A. J. & Halford, S. E. (1999) J. Biol. Chem. 274, 363...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2002
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122161/ https://ncbi.nlm.nih.gov/pubmed/11818524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022346799 |
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