Self-generated DNA termini relax the specificity of SgrAI restriction endonuclease
The primary target of SgrAI restriction endonuclease is a multiple sequence of the form 5′-CPu↓CCGGPyG. Previous work had indicated that SgrAI must bind two recognition sites simultaneously for catalysis [Bilcock, D. T., Daniels, L. E., Bath, A. J. & Halford, S. E. (1999) J. Biol. Chem. 274, 36379–3...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2002
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122161/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11818524/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.022346799 |
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