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Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor.

The lethal factor (LF) produced by toxigenic strains of Bacillus anthracis is a Zn(2+)-endopeptidase that cleaves the mitogen-activated protein kinase kinases (MAPKKs) MEK1, MEK2 and MKK3. Using genetic and biochemical approaches, we have extended the study of LF proteolytic specificity to all known...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Vitale, G, Bernardi, L, Napolitani, G, Mock, M, Montecucco, C
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2000
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221512/
https://ncbi.nlm.nih.gov/pubmed/11104681
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