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Expression and regulation of pyruvate dehydrogenase kinase isoforms in the developing rat heart and in adulthood: role of thyroid hormone status and lipid supply.

Activation of the pyruvate dehydrogenase (PDH) complex (PDHC) promotes glucose disposal, whereas inactivation conserves glucose. The PDH kinases (PDHKs) regulate glucose oxidation through inhibitory phosphorylation of PDHC. The adult rat heart contains three PDHK isoforms PDHK1, PDHK2 and PDHK4. Usi...

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Detaylı Bibliyografya
Asıl Yazarlar: Sugden, M C, Langdown, M L, Harris, R A, Holness, M J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2000
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221511/
https://ncbi.nlm.nih.gov/pubmed/11104680
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