Contrasting effects of alloxan on islets and single mouse pancreatic beta-cells.

Alloxan is used to induce diabetes in animals; however, the underlying mechanisms are still a matter of debate. Alloxan evoked a rapid hyperpolarization of the plasma membrane potential and suppressed electrical activity elicited by 15 mM glucose, thus terminating voltage-dependent Ca(2+) influx. Ac...

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Hlavní autoři: Drews, G, Krämer, C, Düfer, M, Krippeit-Drews, P
Médium: Artigo
Jazyk:Inglês
Vydáno: 2000
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221470/
https://ncbi.nlm.nih.gov/pubmed/11085932
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