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Role for the microtubule cytoskeleton in GLUT4 vesicle trafficking and in the regulation of insulin-stimulated glucose uptake.

Insulin stimulates glucose uptake into adipocytes by promoting the translocation of the glucose transporter isoform 4 (GLUT4) from intracellular vesicles to the plasma membrane. In 3T3-L1 adipocytes GLUT4 resides both in an endosomal pool, together with transferrin receptors, and in a unique pool te...

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Sonraí Bibleagrafaíochta
Main Authors: Fletcher, L M, Welsh, G I, Oatey, P B, Tavaré, J M
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2000
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221456/
https://ncbi.nlm.nih.gov/pubmed/11085918
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