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Conformational changes in activated protein C caused by binding of the first epidermal growth factor-like module of protein S.

The first epidermal growth factor-like module of human plasma protein S (EGF1, residues 76-116) was chemically synthesized and tested for its ability to inhibit the anticoagulant cofactor activity of protein S for the anticoagulant protease, activated protein C (APC). EGF1 completely inhibited the s...

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Detalhes bibliográficos
Main Authors: Hackeng, T M, Yegneswaran, S, Johnson, A E, Griffin, J H
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221202/
https://ncbi.nlm.nih.gov/pubmed/10903136
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