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Regulation of BAD by cAMP-dependent protein kinase is mediated via phosphorylation of a novel site, Ser155.

The interaction of BAD (Bcl-2/Bcl-X(L)-antagonist, causing cell death) with Bcl-2/Bcl-X(L) is thought to neutralize the anti-apoptotic effects of the latter proteins, and may represent one of the mechanisms by which BAD promotes apoptosis. A variety of survival signals are reported to induce the pho...

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Bibliografske podrobnosti
Main Authors: Lizcano, J M, Morrice, N, Cohen, P
Format: Artigo
Jezik:Inglês
Izdano: 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221178/
https://ncbi.nlm.nih.gov/pubmed/10880354
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