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Inhibition of Ca(2+) signalling by p130, a phospholipase-C-related catalytically inactive protein: critical role of the p130 pleckstrin homology domain.

p130 was originally identified as an Ins(1,4,5)P(3)-binding protein similar to phospholipase C-delta but lacking any phospholipase activity. In the present study we have further analysed the interactions of p130 with inositol compounds in vitro. To determine which of the potential ligands interacts...

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Main Authors: Takeuchi, H, Oike, M, Paterson, H F, Allen, V, Kanematsu, T, Ito, Y, Erneux, C, Katan, M, Hirata, M
Formato: Artigo
Idioma:Inglês
Publicado: 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1221157/
https://ncbi.nlm.nih.gov/pubmed/10861248
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