Suppression of cell migration by phospholipase C-related catalytically inactive protein-dependent modulation of PI3K signalling

The metabolic processes of phosphatidylinositol 4,5-bisphosphate [PI(4,5)P(2)] into PI(3,4,5)P(3) and the subsequent PI(3,4,5)P(3) signalling are involved in cell migration. Dysfunctions in the control of this pathway can cause human cancer cell migration and metastatic growth. Here we investigated...

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Udgivet i:Sci Rep
Main Authors: Asano, Satoshi, Taniguchi, Yuri, Yamawaki, Yosuke, Gao, Jing, Harada, Kae, Takeuchi, Hiroshi, Hirata, Masato, Kanematsu, Takashi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511194/
https://ncbi.nlm.nih.gov/pubmed/28710365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05908-7
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