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Ca2+ buffering in the heart: Ca2+ binding to and activation of cardiac myofibrils.

The measurement of cardiac Ca(2+) transients using spectroscopic Ca(2+) indicators is significantly affected by the buffering properties of the indicators. The aim of the present study was to construct a model of cardiac Ca(2+) buffering that satisfied the kinetic constraints imposed by the maximum...

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Autori principali: Smith, G A, Dixon, H B, Kirschenlohr, H L, Grace, A A, Metcalfe, J C, Vandenberg, J I
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220865/
https://ncbi.nlm.nih.gov/pubmed/10677358
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