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The Influence of Ca(2+) Buffers on Free [Ca(2+)] Fluctuations and the Effective Volume of Ca(2+) Microdomains

Intracellular calcium (Ca(2+)) plays a significant role in many cell signaling pathways, some of which are localized to spatially restricted microdomains. Ca(2+) binding proteins (Ca(2+) buffers) play an important role in regulating Ca(2+) concentration ([Ca(2+)]). Buffers typically slow [Ca(2+)] te...

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Hlavní autoři: Weinberg, Seth H., Smith, Gregory D.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4070277/
https://ncbi.nlm.nih.gov/pubmed/24940787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.04.045
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