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Reagent or myeloperoxidase-generated hypochlorite affects discrete regions in lipid-free and lipid-associated human apolipoprotein A-I.

We have previously shown that the modification of high-density lipoprotein subclass 3 (HDL(3)) by HOCl transformed an anti-atherogenic lipoprotein into a high-uptake form for macrophages and caused a significant impairment of cholesterol efflux capacity [Panzenboeck, Raitmayer, Reicher, Lindner, Gla...

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Autores principales: Bergt, C, Oettl, K, Keller, W, Andreae, F, Leis, H J, Malle, E, Sattler, W
Formato: Artigo
Lenguaje:Inglês
Publicado: 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220859/
https://ncbi.nlm.nih.gov/pubmed/10677352
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