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PKQuest: volatile solutes – application to enflurane, nitrous oxide, halothane, methoxyflurane and toluene pharmacokinetics

BACKGROUND: The application of physiologically based pharmacokinetic models (PBPK) to human studies has been limited by the lack of the detailed organ information that is required for this analysis. PKQuest is a new generic PBPK that is designed to avoid this problem by using a set of "standard...

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Detalhes bibliográficos
Autor principal: Levitt, David G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122062/
https://ncbi.nlm.nih.gov/pubmed/12182764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2253-2-5
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