A phosphotyrosine-containing quenched fluorogenic peptide as a novel substrate for protein tyrosine phosphatases.

Mca-Gly-Asp-Ala-Glu-Tyr(PO(3)H(2))-Ala- Ala-Lys(DNP)-Arg-NH(2), where Mca is (7-methoxycoumarin-4-yl)acetyl and DNP is 2,4-dinitrophenyl, was synthesized as a fluorogenic substrate for protein tyrosine phosphatases (PTPs). In the peptide, the fluorescent Mca group is quenched efficiently by the DNP...

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Bibliografski detalji
Glavni autori: Nishikata, M, Suzuki, K, Yoshimura, Y, Deyama, Y, Matsumoto, A
Format: Artigo
Jezik:Inglês
Izdano: 1999
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220565/
https://ncbi.nlm.nih.gov/pubmed/10510304
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