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A single point mutation leads to an instability of the hetero-octameric structure of yeast phosphofructokinase.
Yeast phosphofructokinase is an oligomeric enzyme whose detectable activity in vitro depends on its hetero-octameric structure. Here we provide data demonstrating that an alanine residue at positions 874 (for the PFK1-encoded alpha-subunit) or 868 (for the PFK2-encoded beta-subunit) is crucial to ac...
Gorde:
Egile Nagusiak: | , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
1999
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1220325/ https://ncbi.nlm.nih.gov/pubmed/10377240 |
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