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A conserved RGD (Arg-Gly-Asp) motif in the transferrin receptor is required for binding to transferrin.

The transferrin receptor contains a highly conserved Arg-Gly-Asp (RGD) sequence in the C-terminal region where transferrin is thought to bind. RGD sequences are commonly involved in cell adhesion. This sequence is crucial for transferrin binding, suggesting possible evolutionary links between molecu...

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Bibliographic Details
Main Authors: Dubljevic, V, Sali, A, Goding, J W
Format: Artigo
Language:Inglês
Published: 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220324/
https://ncbi.nlm.nih.gov/pubmed/10377239
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