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Regulation of photoreceptor phosphodiesterase catalysis by its non-catalytic cGMP-binding sites.

The photoreceptor 3':5'-cyclic nucleotide phosphodiesterase (PDE) is the central enzyme of visual excitation in rod photoreceptors. The hydrolytic activity of PDE is precisely regulated by its inhibitory gamma subunit (Pgamma), which binds directly to the catalytic site. We examined the in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: D'Amours, M R, Cote, R H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220321/
https://ncbi.nlm.nih.gov/pubmed/10359674
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