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CAT2-mediated L-arginine transport and nitric oxide production in activated macrophages.

Activated macrophages require l-arginine uptake to sustain NO synthesis. Several transport systems could mediate this l-arginine influx. Using competition analysis and gene-expression studies, amino acid transport system y+ was identified as the major carrier responsible for this activity. To identi...

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Detalhes bibliográficos
Main Authors: Kakuda, D K, Sweet, M J, Mac Leod, C L, Hume, D A, Markovich, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220283/
https://ncbi.nlm.nih.gov/pubmed/10333501
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