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Structure, function and regulation of pyruvate carboxylase.

Pyruvate carboxylase (PC; EC 6.4.1.1), a member of the biotin-dependent enzyme family, catalyses the ATP-dependent carboxylation of pyruvate to oxaloacetate. PC has been found in a wide variety of prokaryotes and eukaryotes. In mammals, PC plays a crucial role in gluconeogenesis and lipogenesis, in...

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Detalhes bibliográficos
Main Authors: Jitrapakdee, S, Wallace, J C
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1220216/
https://ncbi.nlm.nih.gov/pubmed/10229653
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