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Insulin-stimulated kinase from rat fat cells that phosphorylates initiation factor 4E-binding protein 1 on the rapamycin-insensitive site (serine-111).

The effects of insulin and rapamycin on the phosphorylation of the translation regulator, initiation factor 4E-binding protein 1 (4E-BP1) have been studied in rat fat cells by following changes in the incorporation of 32P from [32P]Pi under steady-state conditions. Both unbound 4E-BP1 and 4E-BP1 bou...

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Détails bibliographiques
Auteurs principaux: Heesom, K J, Avison, M B, Diggle, T A, Denton, R M
Format: Artigo
Langue:Inglês
Publié: 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219839/
https://ncbi.nlm.nih.gov/pubmed/9806882
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