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Atypical protein kinase Clambda binds and regulates p70 S6 kinase.

p70 S6 kinase (p70 S6K) has been implicated in the regulation of cell cycle progression. However, the mechanism of its activation is not fully understood. In the present work, evidence is provided that an atypical protein kinase C (PKC) isotype, PKClambda, is indispensable, but not sufficient, for t...

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Bibliographic Details
Main Authors: Akimoto, K, Nakaya, M, Yamanaka, T, Tanaka, J, Matsuda, S, Weng, Q P, Avruch, J, Ohno, S
Format: Artigo
Language:Inglês
Published: 1998
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219797/
https://ncbi.nlm.nih.gov/pubmed/9761742
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