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Transmembrane-truncated alphavbeta3 integrin retains high affinity for ligand binding: evidence for an 'inside-out' suppressor?

The molecular mechanisms of alphavbeta3 integrin affinity regulation have important biological implications in tumour development, wound repair and angiogenesis. We expressed, purified and characterized recombinant forms of human alphavbeta3 (r-alphavbeta3) and compared the activation state of these...

詳細記述

保存先:
書誌詳細
主要な著者: Mehta, R J, Diefenbach, B, Brown, A, Cullen, E, Jonczyk, A, Güssow, D, Luckenbach, G A, Goodman, S L
フォーマット: Artigo
言語:Inglês
出版事項: 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1219217/
https://ncbi.nlm.nih.gov/pubmed/9480902
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