Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3.

5'-Rapid amplification of cDNA ends, done on poly(A)+ RNA from human U87 cells, was used to identify 420 bp of novel 5' sequence of a PDE4B cAMP-specific phosphodiesterase (PDE). This identified an open reading frame encoding a putative 721-residue 'long-form' PDE4B splice varian...

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Main Authors: Huston, E, Lumb, S, Russell, A, Catterall, C, Ross, A H, Steele, M R, Bolger, G B, Perry, M J, Owens, R J, Houslay, M D
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218954/
https://ncbi.nlm.nih.gov/pubmed/9371714
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