Rac1 is required for cell proliferation and G2/M progression.

We have transiently expressed a dominant negative form of rac1 (N17rac1) using adenoviral-mediated gene transfer. The level of N17rac1 expression is demonstrated to be proportional to the multiplicity of infection. Expression of N17rac1 in Rat 2 fibroblasts results in cytostatic growth arrest. Cell-...

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Bibliografiske detaljer
Main Authors: Moore, K A, Sethi, R, Doanes, A M, Johnson, T M, Pracyk, J B, Kirby, M, Irani, K, Goldschmidt-Clermont, P J, Finkel, T
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218631/
https://ncbi.nlm.nih.gov/pubmed/9337845
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