Oligomycin inhibits store-operated channels by a mechanism independent of its effects on mitochondrial ATP.

Inhibitors of mitochondrial oxidative metabolism have been proposed to interfere with Ca2+ influx mediated by store-operated channels (SOC), secondary to their effects on ATP production. We assessed SOC activity by 45Ca2+ influx and fluorimetric measurements of free Ca2+ or Mn2+ quench in thapsigarg...

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Main Authors: Cho, J H, Balasubramanyam, M, Chernaya, G, Gardner, J P, Aviv, A, Reeves, J P, Dargis, P G, Christian, E P
Formato: Artigo
Idioma:Inglês
Publicado: 1997
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218516/
https://ncbi.nlm.nih.gov/pubmed/9210424
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