Inhibition of the expression of ornithine decarboxylase and c-Myc by cell-permeant ceramide in difluoromethylornithine-resistant leukaemia cells.

Ceramide has emerged as a novel lipid mediator in cell growth and apoptosis. In difluoromethylornithine-resistant L1210 cells stimulated to growth from quiescence, the cell-permeant analogues of ceramide N-acetylsphingosine (C2-ceramide) and N-hexanoylsphingosine (C6-ceramide) inhibited the inductio...

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Bibliografiske detaljer
Main Authors: Flamigni, F, Faenza, I, Marmiroli, S, Stanic', I, Giaccari, A, Muscari, C, Stefanelli, C, Rossoni, C
Format: Artigo
Sprog:Inglês
Udgivet: 1997
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218493/
https://ncbi.nlm.nih.gov/pubmed/9210401
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