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Phospholipase C inhibitor, U73122, releases intracellular Ca2+, potentiates Ins(1,4,5)P3-mediated Ca2+ release and directly activates ion channels in mouse pancreatic acinar cells.

It is recognized in many cellular systems that the receptor/G-protein activation of phospholipase C and Ins(1,4,5)P3 production is the transduction pathway regulating the release of Ca2+ from internal stores. Ca2+ signals can now be monitored at the level of single cells but the biochemical detectio...

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Detaylı Bibliyografya
Asıl Yazarlar: Mogami, H, Lloyd Mills, C, Gallacher, D V
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1997
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218477/
https://ncbi.nlm.nih.gov/pubmed/9182729
Etiketler: Etiketle
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