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Evidence against an early signalling role for ceramide in Fas-mediated apoptosis.

We have investigated whether the increases in ceramide levels that occur during apoptosis in SKW 6.4 cells induced by anti-Fas antibody depend on the activation of caspases. Using cells prelabelled to equilibrium with [14C]acetate, it was shown that the amount of ceramide approximately doubled after...

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Hlavní autoři: Sillence, D J, Allan, D
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218397/
https://ncbi.nlm.nih.gov/pubmed/9164837
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