cAMP prevents the glucose-mediated stimulation of GLUT2 gene transcription in hepatocytes.

Glucose homoeostasis necessitates the presence in the liver of the high Km glucose transporter GLUT2. In hepatocytes, we and others have demonstrated that glucose stimulates GLUT2 gene expression in vivo and in vitro. This effect is transcriptionally regulated and requires glucose metabolism within...

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Bibliografiska uppgifter
Huvudupphovsmän: Rencurel, F, Waeber, G, Bonny, C, Antoine, B, Maulard, P, Girard, J, Leturque, A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1997
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1218210/
https://ncbi.nlm.nih.gov/pubmed/9065761
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