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Proteinases are isoform-specific regulators of the binding of transforming growth factor beta to alpha 2-macroglobulin.

alpha 2-Macroglobulin (alpha 2M) regulates growth and gene expression in many cell types by binding and neutralizing transforming growth factor beta (TGF-beta). In this study we characterized the effects of the serine proteinase, plasmin, on the interaction of alpha 2M with TGF-beta 1 and TGF-beta 2...

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Autors principals: Webb, D J, Weaver, A M, Atkins-Brady, T L, Gonias, S L
Format: Artigo
Idioma:Inglês
Publicat: 1996
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217964/
https://ncbi.nlm.nih.gov/pubmed/8973565
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