Binding of transforming growth factor-beta 1 to methylamine-modified alpha 2-macroglobulin and to binary and ternary alpha 2-macroglobulin-proteinase complexes.

The binding of 125I-labelled transforming growth factor-beta 1 (TGF-beta 1) to human alpha 2-macroglobulin (alpha 2M) was studied by native PAGE and autoradiography. TGF-beta 1 bound preferentially to alpha 2M-methylamine and minimally, if at all, to native alpha 2M. Preparations of alpha 2M-protein...

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Detalhes bibliográficos
Main Authors: Hall, S W, LaMarre, J, Marshall, L B, Hayes, M A, Gonias, S L
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1130723/
https://ncbi.nlm.nih.gov/pubmed/1371050
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