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Synthetic hydrophobic peptides are substrates for P-glycoprotein and stimulate drug transport.

P-Glycoprotein functions as an ATP-driven active efflux pump for many natural products and chemotherapeutic drugs. Hydrophobic peptides have been shown to block drug uptake by P-glycoprotein, indicating that they might be transport substrates. The present study examines the interaction of the synthe...

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Hlavní autoři: Sharom, F J, Yu, X, DiDiodato, G, Chu, J W
Médium: Artigo
Jazyk:Inglês
Vydáno: 1996
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1217947/
https://ncbi.nlm.nih.gov/pubmed/8973548
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